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Corporate office of Medis International a.s. in the Czech Republic is located in Prague; Production and Dispatching in Bolatice near Opava.

Medis International a.s.
Production plant Bolatice
Průmyslová 961/16
747 23 Bolatice
Czech Republic
tel.: +420 553 038 770
fax:+420 595 171 564
e-mail info@medisinternational.cz

Blistered tablets

Medis Bolatice

Production

The manufacturing facility was designed and constructed in accordance with the latest requirements of Good Manufacturing Practice (GMP) for manufacturing of pharmaceuticals.

Manufacturing Plant

The manufacturing plant has 2 floors:
- On the ground floor: manufacturing premises for primary and secondary packaging, physicochemical and microbiological laboratories, manufacturing personnel changing rooms, offices and sanitary facilities are situated
- On the first floor: an air-conditioning system, a gas-fired boiler room and an archive room for storing documentation are situated
- An air-conditioned warehouse of the total height 8.8 m for storing of raw materials, intermediate products and finished products is situated in the rear part of the building.

Manufacturing Premises

Manufacturing premises have been designed with the aim to provide the maximum protection of products, personnel and the environment with adherence to rules and requirements of Good Manufacturing Practice in production of pharmaceuticals.
- Clean rooms intended for packaging into primary containers provide 100% air exchange and air filtration through HEPA filters H13
- Material and personnel air-locks are operated at positive overpressure against the adjacent rooms
- Other rooms are equipped with efficient air-conditioning of ISO 9 class
- Manufacturing personel have spacious changing rooms with sanitary facilities available
- An air-conditioned warehouse is equipped with racks for vertical storing of 6 pallets and a handling system working on the basis of barcodes; the overall capacity of the warehouse is 1250 pallet places.

Manufacturing Equipment

In the manufacturing premises, a fully automated blistering and packaging line made by Uhlmann A.G. Germany with a capacity of 220 mio.of tablets or capsules per shift, per year is installed. Additioinal rooms are complete and ready for installation of 3 packaging lines, whenever further capacity is required.
Primary packaging is performed in blistering machine Uhlmann B 1240/1647 which enables filling of five parallel lines with the maximum width of foil 168 mm, with the maximum capacity of 350 blisters/min.
The line is equipped with a camera control system with a Microchrom camera for colour detection.
The installed blistering machine B1240/1647 enables blistering of tablets and capsules (both soft and hard) in all types of foils: PVC, PP, PVC/PVDC, PVC/PE/PVDC, PVC/Aclar and Alu/Alu blisters.
Manufacturing Equipment Medis - Bolatice
Secondary packaging is performed using a cardboard-packing machine Uhlmann C 2155/233 with the max. packaging speed up to 150 cartons/min (max. 400 blisters/min). The line is equipped with an automated control system, including checking of Pharma codes on the containers and patient information leaflet.
The line is also equipped with a control balance LL120-XS2/716 for checking of up to 200 cartons/min with the max. weight 300 g.

The final part of the line is a strapping machine S 3025/129 with the maximum capacity 300 packages/min, enabling strapping with PE foil of the max. width 150 mm.
Manufacturing Equipment Medis - Bolatice

Our Technology:

A fully automated blistering and packaging line made by Uhlmann A.G. Germany with a capacity of 220 mio. of tablets or capsules per year has been installed.

The installed blistering machine B1240/1647 enables blistering of tablets and capsules (both soft and hard) in all types of foils: PVC, PP, PVC/PVDC, PVC/Aclar and Alu/Alu blisters.

blistering machine B1240/1647